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28-Jul-2000
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Arch Hellen Med, 16(6), November-December 1999, 602–604
SHORT COMMUNICATION
Ôhe use of gabapentin in the treatment
of a patient
with bipolar disorder and hepatic dysfunction
V. BOZIKAS, P. PETRIKIS, C. PHOCAS, A. KARAVATOS
1st Psychiatric Clinic, Aristotle
University of Thessaloniki, Greece
Gabapentin is a new antiepileptic drug which is used mainly as an adjunctive medicine in the treatment of refractory acute mania. It is not metabolized by the liver but is excreted unchanged in the urine, so it has no effects on the hepatic enzymes. We present the case of a patient with bipolar disorder and hepatic dysfunction caused by HCV infection, in the treatment of whom the specific pharmacokinetic properties of gabapentin proved useful.
Key words: Bipolar disorder, Gabapentin, HCV infection.
