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11-Nov-2024
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Arch Hellen Med, 41(6), November-December 2024, 755-760 ORIGINAL PAPER Review of 45 gastrointestinal stromal tumors treated in a Brazilian hospital L.A.M. dos Santos,1 V.M. dos Santos,2 V. Grigoli,1 L.S.V. de Miranda3 |
OBJECTIVE Review of clinicopathological features, diagnostic tools, complications, management, and outcomes of 45 gastrointestinal stromal tumors (GISTs) treated in 43 Brazilian patients.
METHOD Analysis of records from a single hospital between 2015 and 2020 about management by video laparoscopy, and clinical, adjuvant, or neoadjuvant therapy; prognostic factors after resection including size, stage, mitotic count, free margin, complications, and the recurrence of the tumors.
RESULTS Twenty-nine patients were women and the global mean age was 62.42±12.27 years. The sites of GISTs were: stomach (69.0%), jejunum and ileum (17.8%), and extra-gastrointestinal (13.2%). Tumor sizes were: <2 cm (24.4%), 2.0–3.8 cm (31.0%), 4.0–5.2 cm (9.0%), 7.0–9.5 cm (15.6%), 10.0–17.0 cm (13.3%), and 25.0–35.0 cm (6.7%), with fusiform (93.0%) and mixed (7.0%) cellularity. Video laparoscopic surgery treated 40% of cases, and four were for recidivism; adjuvant (57.8%) and neoadjuvant (2.2%) chemotherapies were utilized. The postoperative course was unremarkable in 20.0%, and infections occurred in 6.6% of the cases.
CONCLUSIONS As a whole, the findings of the present review of cases are in accordance with the literature.
Key words: Diagnosis, Gastrointestinal stromal tumor, Immunohistochemistry, Management.
