Last update:
   23-Jan-2024
 

Arch Hellen Med, 41(1), January-February 2024, 17-24

REVIEW

The role of anti-Müllerian hormone (AMH) in reproductive physiology and assisted reproduction

Ι. Legakis,1,2 P. Psathas,2,3 K. Kostaras,2,3 G. Chrousos4
1European University of Cyprus, Nicosia, Cyprus,
2ΙASO Group of Hospitals, Athens,
3Assisted Reproduction Unit (IVF), Institute of Life – IASO, Athens,
4First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Athens, Greece

Societal changes regarding the role of women have significant impacts on women's willingness to have children and the timing of childbearing. Ovarian reserve in women typically begins to decline at the age of 35, and accurate estimation is a prerequisite. In this review, we discuss the dynamics of circulating anti-Müllerian hormone (AMH) that remarkably vary with sex and age and summarize the role of AMH in female reproductive physiology and provide evidence of higher accuracy in predicting ovarian response to stimulation. Furthermore, AMH-guided ovarian stimulation can lead to individualization of therapeutic strategies for infertility treatment.

Key words: Anti-Müllerian hormone, Assisted reproduction, Infertility.

© Archives of Hellenic Medicine