Last update:
   03-Jun-2020
 

Arch Hellen Med, 37(3), May-June 2020, 414-417

SHORT REVIEW

Atypical antipsychotics as adjunctive medication to antidepressants for nonpsychotic depression
R. Gournellis,1 I. Michopoulos,1 D. Ploumpidis,2 P. Skapinakis3
1Second Department of Psychiatry, NKUA "Attikon" University General Hospital, National and Kapodistrian University of Athens, Athens,
2Hellenic Psychiatric Association, Athens,
3Department of Psychiatry, University of Ioannina, School of Medicine, Ioannina, Greece

Small doses of atypical antipsychotics as an adjunctive treatment of depression are efficacious in reducing depressive symptoms with small-to-moderate sized benefits, as shown by evidence-based meta-analyses of numerous studies. Ηowever, atypical antipsychotics should be administered with caution because of their adverse side effects.

Key words: Adjunctive therapy, Antipsychotics, Depression, Guidelines.

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